Medik8 Exo-PDRN Prismatic+: The Next Generation Skin Rejuvenation Serum Has Arrived
Medik8 Exo-PDRN Prismatic+: The Next Generation Skin Rejuvenation Serum Has Arrived
If you have been curious about the exosome and PDRN skincare trend that has taken over professional clinic menus, Medik8 has just made it accessible at home. Exo-PDRN Prismatic+ is the brand's most advanced serum to date, bringing together technology once reserved for medi-spas and professional treatments in a single daily serum. The result? Clinically proven to reduce the visible age of skin by 5 years in just 28 days.
Here is everything you need to know.
What Is Medik8 Exo-PDRN Prismatic+?
Exo-PDRN Prismatic+ is a next-generation skin rejuvenation serum built around three breakthrough technologies: Prismatic PDRN, a Triple Exosome Complex, and a Growth Factor MiniProtein. Together, these work to address what Medik8 calls the 3 Rs of Rejuvenation: Recover, Restore and Recharge.
Rather than targeting one skin concern, this formula is designed to support the skin's own natural biology across six clinically proven signs of rejuvenation simultaneously:
- Healthier-looking skin
- More even skin tone
- Restored volume
- Visibly reduced wrinkles
- Returned luminosity
- Resilient, firm-feeling skin
RRP: $160.00 / 30ml — available exclusively at authorised Medik8 stockists including Absolute Skin.
The Key Ingredients Explained
Prismatic PDRN
PDRN (Polydeoxyribonucleotide) is a DNA-derived ingredient long used in clinical and medi-spa treatments for its powerful skin recovery properties. Medik8's version is vegan-derived and features a unique stable tetrahedral (prismatic) structure that allows for superior skin penetration compared to standard single-chain PDRN. It works to support skin recovery, calm visible redness and reveal smoother, more youthful-looking skin.
Triple Exosome Complex
Where most exosome serums on the market use a single source of exosomes, Medik8 uses three distinct sources, each with a targeted function:
- Activating Pomegranate Phyto Exosomes — wake the skin up by supporting communication and energy processes
- Postbiotic Exosomes (from Lactobacillus fermentation) — visibly reduce redness, soothe and support the skin's natural barrier
- Restoring Centella Asiatica Phyto Exosomes — protect and promote skin recovery
Importantly, Exo-PDRN Prismatic+ delivers up to 151 billion exosomes per bottle, compared to the millions or low billions found in competitor products. And unlike some exosome serums, it contains no spicules, making it suitable for sensitive skin and safe to use post-treatment.
Growth Factor MiniProtein
Supports the skin's natural collagen, elastin and hyaluronic acid processes over time, visibly smoothing the appearance of wrinkles and improving skin structure.
Supporting Ingredients
- Amino Acids — provide building blocks for the skin's rejuvenation processes
- ATP Precursor — supports the skin's energy processes to help optimise visible rejuvenation
- Low Molecular Weight Hyaluronic Acid — delivers deep hydration throughout the skin's layers for a visibly nourished, supple complexion
The Clinical Evidence
Exo-PDRN Prismatic+ is backed by strong clinical data:
- Reduces visible skin age by 5 years in 28 days (based on elasticity testing on 60 volunteers)
- Boosts skin's natural rejuvenation by +50% (ex vivo regeneration study measuring Ki67 protein markers)
Who Is It For?
Exo-PDRN Prismatic+ is ideal for anyone looking to address multiple visible signs of ageing and wanting results that bridge the gap between professional clinic treatments and at-home maintenance. It suits all skin types including sensitive skin, dry skin and oily skin, and is fragrance-free and non-comedogenic.
If you are someone who invests in professional treatments like facials, peels or laser, this serum is the perfect companion to use at home to support and extend your results.
How to Use Medik8 Exo-PDRN Prismatic+
Apply morning and evening after cleansing. Massage 1-2 pumps across the face, neck and décolletage and allow to absorb for a few seconds before layering other products. Use it as your first serum in your routine.
AM Routine
- Cleanse
- Exo-PDRN Prismatic+
- Additional serums (e.g. Liquid Peptides Advanced MP)
- SPF
PM Routine
- Cleanse
- Exo-PDRN Prismatic+
- Crystal Retinal
- Advanced Pro-Collagen+ Peptide Cream
Each bottle provides approximately 80 applications.
Best Paired With
Advanced Pro-Collagen+ Peptide Cream — the ultimate longevity duo. Supports the foundations of skin longevity with results starting in 7 days, while Exo-PDRN Prismatic+ drives long-term rejuvenation and recovery.
Liquid Peptides Advanced MP — the age-defying duo. Liquid Peptides targets expression lines and visible wrinkle reduction while Exo-PDRN Prismatic+ works on skin resilience and recovery.
Why Exo-PDRN Prismatic+ Stands Out
| Medik8 | Other Brands | |
|---|---|---|
| PDRN type | Next-gen prismatic (tetrahedral, superior penetration) | Standard single-chain PDRN |
| Exosome sources | Triple (3 distinct sources) | Single source |
| Exosome count | Up to 151 billion per bottle | Millions to low billions |
| Spicules | No — suitable for sensitive + post-treatment skin | Some contain spicules |
Shop Medik8 Exo-PDRN Prismatic+ at Absolute Skin
Exo-PDRN Prismatic+ is now available at Absolute Skin. At $160 for 30ml (80 applications), it delivers clinical-grade technology at a fraction of the cost of in-clinic treatments.
Ready to unlock your skin's youthful potential? Shop Medik8 Exo-PDRN Prismatic+ here.
Results based on instrumental tests and clinical studies. Individual results may vary.